Nicotine is a highly addictive substance found in cigarettes, vaping devices, smokeless tobacco, pouches, and other smoking products. It’s often used as a quick fix for stress relief or improved focus. However, research suggests there’s a potential deeper connection between nicotine use and mental health — especially when it comes to anxiety.
But does nicotine cause anxiety? And by association, does vaping cause anxiety? In this article, we’ll explore the link between nicotine and anxiety and shed light on the science behind these questions.
The Link Between Nicotine and Anxiety
The American Psychology Association (APA) defines anxiety as a mental state characterized by feelings of unease, worry, or fear. Though anxiety is a natural part of our lives, chronic anxiety can disrupt daily life.
In the short term, nicotine is often used as a stress reliever or to improve focus. Nicotine consumption stimulates the release of dopamine , AKA the “feel-good” hormone, which temporarily improves mood and focus. However, as the effects wear off, stress and anxiety frequently return — sometimes more intensely — leading to a cycle of nicotine dependency as users try to manage emotional lows.
Over time, nicotine use can cause lasting damage to the brain and body. Studies show it may impair memory, disrupt sleep, and potentially worsen anxiety disorders. Long-term use may also lead to nicotine dependence . Dependence can develop as the brain starts relying on nicotine for balance, leading to withdrawal symptoms like irritability, restlessness, and heightened anxiety when nicotine levels drop.
Nicotine and the Brain's Stress Response
Nicotine triggers the release of dopamine and serotonin , key neurotransmitters that regulate mood and emotions. Dopamine creates a sense of pleasure and reward, while serotonin (also known as the “happy” hormone) helps, which is responsible for regulating mood and emotions. When exposed to nicotine over a long period, the brain begins to experience a craving-and-withdrawal effect , which can eventually turn into nicotine dependency. This dependency can lead to a cycle where nicotine is needed for emotional stability and where absence can create mood swings and heightened anxiety.
Nicotine also activates the body’s fight-or-flight response by stimulating the autonomic nervous system . This triggers adrenaline release , raising heart rate and blood pressure. While this temporary boost may feel energizing, it adds stress to the body. Over time, frequent activation of this mechanism can heighten feelings of tension and unease, which can contribute to long-term anxiety issues.
When nicotine levels drop, withdrawal symptoms like irritability, restlessness, and heightened stress emerge. The brain struggles to balance neurotransmitters without nicotine, intensifying anxiety. This withdrawal-driven discomfort reinforces the urge to consume nicotine, which perpetuates a harmful cycle of dependency.
Is Nicotine use a Cause or Symptom of Anxiety?
The link between nicotine use and anxiety is a bit of a chicken-and-egg scenario.
Research suggests that individuals with anxiety or depression are significantly more likely to use nicotine as a way to relieve stress from overwhelming emotions. Nicotine’s quick release of dopamine can temporarily improve mood, which gives the illusion of control over anxiety. With repeated use, nicotine and anxiety start feeding into each other.
In a way, nicotine use is both a symptom and a cause of anxiety.
Can Vaping Cause Anxiety?
Yes, vaping can contribute to anxiety due to the effects of nicotine on the brain and body. Even though vaping is marketed as a “safer” alternative to smoking, many vape products still contain nicotine. Just like with cigarettes, vaping can lead to nicotine dependency and withdrawal symptoms such as irritability, restlessness, and anxiety.
Another concerning aspect of vaping is its accessibility among the youth . Since it’s marketed with a wide range of enticing flavors and designs, vaping is more appealing to the younger crowd. This makes them more vulnerable to the risks of nicotine dependence and anxiety at an earlier age.
Why do People use Nicotine for Stress Relief When it Causes More Stress?
Many people turn to nicotine because it’s a quick way to relieve stress . Just a few puffs can trigger feelings of relief and relaxation. Instant gratification makes it an easy go-to during stressful moments, even though the effects are short-lived.
Over time, regular nicotine use often leads to dependence and increased tolerance. The brain begins to rely on nicotine for emotional stability, requiring higher amounts to achieve the same relief. This cycle of dependency and withdrawal can worsen stress and anxiety between uses, which makes quitting even harder.
Another reason nicotine remains a go-to is its accessibility and affordability. Compared to stress-relief options like therapy or exercise, nicotine products are convenient and easy to obtain. This convenience can make them more appealing despite healthier alternatives providing more effective and longer-lasting changes.
How to Quit Vaping
Quitting vaping isn’t easy– especially when you do it alone. Jones FDA-approved NRT mints and app can support your journey with judgment-free, personalized guidance.
Our FDA-approved nicotine mints are formulated to curb your nicotine cravings and reduce your dependency over time. With low-addictive potential, these aren't another nicotine product to get you hooked. In fact, they are FDA-approved to help you quit and backed by decades of clinical studies.
Pair NRT mints with our free app that provides clinically proven behavioral strategies and daily motivation. This combination of NRT and community-driven behavioral tools is the most effective way to quit. Our program is designed to help you gradually manage cravings and reduce your nicotine dependency over time.
To get started, take our dependency quiz to receive a personalized quit plan.